The injured brain

Editorial: Monitoring Pathophysiology in the Injured Brain

1 Division of Neurosurgery, Department of Clinical Neurosciences, University of Cambridge, Cambridge Biomedical Campus, Cambridge, United Kingdom, 2 Department of Clinical Neuroscience, Karolinska Institute, Stockholm, Sweden, 3 Department of Physiology and Pharmacology, Section of Perioperative Medicine and Intensive Care, Karolinska Institute, Stockholm, Sweden, 4 Skane University Hospital, D...

Biochemical changes in the injured brain

Brain metabolism is an energy intensive phenomenon involving a wide spectrum of chemical intermediaries. Various injury states have a detrimental effect on the biochemical processes involved in the homeostatic and electrophysiological properties of the brain. The biochemical markers of brain injury are a recent addition in the armamentarium of neuro-clinicians and are being increasingly used in...

Cerebral Palsy and the Brain Injured Child

Cerebral Palsy is a term that encompasses many etiological factors in children diagnosed in utero to age fourteen. Problems may present in utero, peri-natal, and post-natal. Infections, traumatic brain injury, near-drowning, and strokes in children suffering from neurological problems come under the heading of Cerebral Palsy. Hyperbaric oxygenation not only relieves hypoxia but also jumpstarts ...

Compensatory Neurogenesis in the Injured Adult Brain

Monitoring the injured brain: ICP and CBF.

Raised intracranial pressure (ICP) and low cerebral blood flow (CBF) are associated with ischaemia and poor outcome after brain injury. Therefore, many management protocols target these parameters. This overview summarizes the technical aspects of ICP and CBF monitoring, and their role in the clinical management of brain-injured patients. Furthermore, some applications of these methods in curre...